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Identifying insomnia-related chemicals through integrative analysis of genome-wide association studies and chemical-genes interaction information.

Sleep - 14 Sept 2020

Kafle Om Prakash, Cheng Shiqiang, Ma Mei, Li Ping, Cheng Bolun, Zhang Lu, Wen Yan, Liang Chujun, Qi Xin, Zhang Feng

Abstract excerpt

STUDY OBJECTIVES: Insomnia is a common sleep disorder and constitutes a major issue in modern society. We provide new clues for revealing the association between environmental chemicals and insomnia. METHODS: Three genome-wide association studies (GWAS) summary datasets of insomnia (n = 113,006, n = 1,331,010, and n = 453,379, respectively) were driven from the UK Biobank, 23andMe, and deCODE. The chemical-gene...

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PMID: 32170308
DOI: 10.1093/sleep/zsaa042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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