Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRAF V600E mutational load as a prognosis biomarker in malignant melanoma.

PloS one - 1 Jan 2020

Sevilla Arrate, Morales M Celia, Ezkurra Pilar A, Rasero Javier, Velasco Verónica, Cancho-Galan Goikoane, Sánchez-Diez Ana, Mujika Karmele, Penas Cristina, Smith Isabel, Asumendi Aintzane, Cortés Jesús M, Boyano Maria Dolores, Alonso Santos

Abstract excerpt

Analyzing the mutational load of driver mutations in melanoma could provide valuable information regarding its progression. We aimed at analyzing the heterogeneity of mutational load of BRAF V600E in biopsies of melanoma patients of different stages, and investigating its potential as a prognosis factor. Mutational load of BRAF V600E was analyzed by digital PCR in 78 biopsies of melanoma patients of different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Machine Learning

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Melanoma

Share to Melanoma, Cutaneous Malignant

Share to Neoplasm Metastasis

Share to Nevus, Pigmented

Share to Proto-Oncogene Proteins B-raf

Share to Skin Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 32168325
DOI: 10.1371/journal.pone.0230136
PMCID: PMC7069620

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRAF V600E mutational load as a prognosis biomarker in malignant melanoma.PMID 32168325Read ↗

Dissecting the Spectrum of Rare BRAF Mutations in Melanoma: A Nation-Wide Study by the Italian Melanoma Intergroup (IMI).Semantic proximity Read ↗

BRAF V600E Mutation in Malignant Melanoma-A Romanian Research Experience.Semantic proximity Read ↗

Molecular testing for BRAF mutations to inform melanoma treatment decisions: a move toward precision medicineSemantic proximity Read ↗

Current Controversies and Challenges on BRAF V600K-Mutant Cutaneous MelanomaSemantic proximity Read ↗

High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients.Semantic proximity Read ↗

Variables that influence BRAF mutation probability: A next-generation sequencing, non-interventional investigation of BRAFV600 mutation status in melanoma.Semantic proximity Read ↗

Clinical characteristics and treatment outcomes of non-V600 E/K BRAF mutant melanoma patients: a single-institution experience.Semantic proximity Read ↗

Non-V600E/K BRAF Mutations in Metastatic Melanoma: Molecular Description, Frequency, and Effectiveness of Targeted Therapy in a Large National Cohort.Semantic proximity Read ↗

Braf V600E mutation in melanoma: translational current scenario.Semantic proximity Read ↗

BRAF Mutation Heterogeneity in Melanoma Lesions.Semantic proximity Read ↗

The \textit{BRAF} V600E mutation in single- institution study of Russian melanoma patients.Semantic proximity Read ↗

The evolving universe of BRAF mutations in melanoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.