Article
LOX gene polymorphisms are associated with osteoporotic vertebral compression fracture in postmenopausal Chinese women.
Gene - 30 May 2020
Xiao Wenjin, He Jinwei, Fu Wenzhen, Xu Youjia, Zhang Zhenlin
Abstract excerpt
INTRODUCTION: Collagen cross-linking, which is regulated by lysyl oxidase (LOX), plays critical roles in bone mechanical strength. LOX can influence bone remodeling by modulating osteoblast and osteoclast activity. This study aimed to explore the effect of LOX gene polymorphisms on osteoporotic fractures susceptibility in postmenopausal Chinese women. METHODS: This was a prospective study of postmenopausal women...
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