Article
Functional metabolomics as a tool to analyze Mediator function and structure in plants.
PloS one - 1 Jan 2017
Davoine Celine, Abreu Ilka N, Khajeh Khalil, Blomberg Jeanette, Kidd Brendan N, Kazan Kemal, Schenk Peer M, Gerber Lorenz, Nilsson Ove, Moritz Thomas, Björklund Stefan
Abstract excerpt
Mediator is a multiprotein transcriptional co-regulator complex composed of four modules; Head, Middle, Tail, and Kinase. It conveys signals from promoter-bound transcriptional regulators to RNA polymerase II and thus plays an essential role in eukaryotic gene regulation. We describe subunit localization and activities of Mediator in Arabidopsis through metabolome and transcriptome analyses from a set of Mediator...
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