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Article

Phenotypic testing of patient herpes simplex virus type 1 and 2 isolates for acyclovir resistance by a novel method based on real-time cell analysis.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2020

Caliaro Oliver, Barbani Maria Teresa, Klenja Shkipe, Morfin Florence, Frobert Emilie, Gorgievski Meri, Steinlin-Schopfer Jacqueline, Suter-Riniker Franziska

Abstract excerpt

BACKGROUND: Acyclovir (ACV) is the most commonly used drug for herpes simplex virus (HSV) infection therapy. Prolonged antiviral therapy or prophylaxis in immunocompromised patients may promote the development of drug-resistant strains. Due to the high polymorphism in genes involved in drug resistance, phenotypic methods, although work-intensive, are still required to test drug susceptibility. Real-time cell...

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Identifiers

PMID: 32163870
DOI: 10.1016/j.jcv.2020.104303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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