The contributions of multidrug resistant clones to the success of pandemic extra-intestinal Pathogenic Escherichia coli

Abstract excerpt

Introduction High-risk multidrug (MDR) clones have played essential roles in the global emergence and spread of antimicrobial resistance (AMR), especially among Extra-intestinal Escherichia coli (ExPEC).Areas covered Successful global ExPEC MDR clones are linked with the acquisition of fluoroquinolone resistance, CTX-M enzymes, and with carbapenemases. This article described the underlying mechanisms of...