Article
Molecular and therapeutic advances in the diagnosis and management of malignant pheochromocytomas and paragangliomas.
The oncologist - 1 Jan 2013
Lowery Aoife J, Walsh Siun, McDermott Enda W, Prichard Ruth S
Abstract excerpt
Pheochromocytomas (PCCs) and paragangliomas (PGLs) are rare catecholamine-secreting tumors derived from chromaffin cells originating in the neural crest. These tumors represent a significant diagnostic and therapeutic challenge because the diagnosis of malignancy is frequently made in retrospect by the development of metastatic or recurrent disease. Complete surgical resection offers the only potential for cure;...
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