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Article

Molecular endotypes of type 1 and type 2 SLE

1 Jan 2023

Abstract excerpt

OBJECTIVE: To character the molecular landscape of patients with type 1 and type 2 SLE by analysing gene expression profiles from peripheral blood. METHODS: Full transcriptomic RNA sequencing was carried out on whole blood samples from 18 subjects with SLE selected by the presence of manifestations typical of type 1 and type 2 SLE. The top 5000 row variance genes were analysed by Multiscale Embedded Gene...

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PMID: 36720488
DOI: 10.1136/lupus-2022-000861

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