Article
Gene amplification as a form of population-level gene expression regulation.
Nature ecology & evolution - 1 Apr 2020
Tomanek I, Grah R, Lagator M, Andersson A M C, Bollback J P, Tkačik G, Guet C C
Abstract excerpt
Organisms cope with change by taking advantage of transcriptional regulators. However, when faced with rare environments, the evolution of transcriptional regulators and their promoters may be too slow. Here, we investigate whether the intrinsic instability of gene duplication and amplification provides a generic alternative to canonical gene regulation. Using real-time monitoring of gene-copy-number mutations in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.