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Article

Real-time evolution of new genes by innovation, amplification, and divergence.

Science (New York, N.Y.) - 19 Oct 2012

Näsvall Joakim, Sun Lei, Roth John R, Andersson Dan I

Abstract excerpt

Gene duplications allow evolution of genes with new functions. Here, we describe the innovation-amplification-divergence (IAD) model in which the new function appears before duplication and functionally distinct new genes evolve under continuous selection. One example fitting this model is a preexisting parental gene in Salmonella enterica that has low levels of two distinct activities. This gene is amplified to...

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Identifiers

PMID: 23087246
DOI: 10.1126/science.1226521
PMCID: PMC4392837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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