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ENOS polymorphisms in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy in a Chinese Han population.

Ophthalmic genetics - 1 Dec 2016

Zuo Chengguo, Li Meng, Zhang Xiongze, Chen Hui, Su Yu, Wu Kunfang, Wen Feng

Abstract excerpt

PURPOSE: To investigate whether common genetic variants in the endothelial nitric oxide synthase gene (eNOS) are associated with neovascular age-related macular degeneration (nAMD) and polypoidal choroidalvasculopathy (PCV) in a Chinese Han population. METHODS: DNA samples were obtained from 157 nAMD patients, 250 PCV patients and 204 healthy control subjects. Tag single nucleotide polymorphisms (SNPs) across the...

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PMID: 26914548
DOI: 10.3109/13816810.2015.1107598

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