Article
Identification of PGF as a New Gene for Neovascular Age-Related Macular Degeneration in a Chinese Population.
Investigative ophthalmology & visual science - 1 Apr 2016
Chen Li Jia, Ma Li, Chu Wai Kit, Lai Timothy Y Y, Chen Haoyu, Brelén Mårten E, Rong Shi Song, Young Alvin L, Tam Pancy O S, Zhang Mingzhi, Pang Chi Pui
Abstract excerpt
PURPOSE: To determine the associations of the VEGFA, VEGFB, and placental growth factor (PGF) genes with neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy (PCV). METHODS: Seven single-nucleotide polymorphisms (SNPs) in VEGFA, three SNPs in VEGFB, and five SNPs in PGF were genotyped in 1722 unrelated Chinese participants, including a Hong Kong cohort of 214 nAMD patients,...
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