Article
COL1A2 polymorphic markers confer an increased risk of neovascular age-related macular degeneration in a Han Chinese population.
Molecular vision - 1 Jan 2012
Zuo Chengguo, Wen Feng, Li Meng, Zhang Xiongze, Chen Hui, Wu Kunfang, Zeng Renpan
Abstract excerpt
PURPOSE: We have previously documented that neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy (PCV) have multiple different clinical and genetic characteristics. In this study, we investigated the association of rs42524 in the alpha-2 type I collagen (COL1A2) gene, which has been identified as a risk variant for intracranial aneurysm, with nAMD and PCV in a Han Chinese...
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