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Article

The role of REST/NRSF, TrkB and BDNF in neurobiological mechanisms of different susceptibility to seizure in a PTZ model of epilepsy.

Brain research bulletin - 1 May 2020

Chmielewska Natalia, Wawer Adriana, Maciejak Piotr, Turzyńska Danuta, Sobolewska Alicja, Skórzewska Anna, Osuch Bartosz, Płaźnik Adam, Szyndler Janusz

Abstract excerpt

Global transcriptional disturbances are believed to play a major role in the course of epilepsy. Due to the high complexity, the neurobiological mechanisms underlying different susceptibility to seizure and epilepsy are not well known. A transcription factor called REST/NRSF (repressor element 1-silencing transcription factor/neuron-restrictive silencer factor) is believed to contribute to processes associated...

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Identifiers

PMID: 32151715
DOI: 10.1016/j.brainresbull.2020.03.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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