Article
Animal models of drug-resistant epilepsy.
Novartis Foundation symposium - 1 Jan 2002
Löscher Wolfgang
Abstract excerpt
It is not known why and how epilepsy becomes drug resistant in 20-30% of patients, while other patients with seemingly identical seizure types can achieve control of seizures with medication. An animal model of epilepsy allowing selection of pharmacoresistant and pharmacosensitive subgroups of animals would be a valuable tool to study mechanisms of pharmacoresistance and to develop more effective treatment...
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