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Epigenome-wide association study of global cortical volumes in generation Scotland: Scottish family health study.

Epigenetics - 1 Oct 2022

Barbu Miruna Carmen, Harris Mat, Shen Xueyi, Aleks Stolicyn, Green Claire, Amador Carmen, Walker Rosie, Morris Stewart, Adams Mark, Sandu Anca, McNeil Christopher, Waiter Gordon, Evans Kathryn, Campbell Archie, Wardlaw Joanna, Steele Douglas, Murray Alison, Porteous David, McIntosh Andrew, Whalley Heather

Abstract excerpt

A complex interplay of genetic and environmental risk factors influence global brain structural alterations associated with brain health and disease. Epigenome-wide association studies (EWAS) of global brain imaging phenotypes have the potential to reveal the mechanisms of brain health and disease and can lead to better predictive analytics through the development of risk scores.We perform an EWAS of global brain...

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Identifiers

PMID: 34738878
DOI: 10.1080/15592294.2021.1997404
PMCID: PMC9542280

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