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Effects of Platelet Count on Blood Pressure: Evidence from Observational and Genetic Investigations

18 Dec 2023

Abstract excerpt

Platelet count has been associated with blood pressure, but whether this association reflects causality remains unclear. To strengthen the evidence, we conducted a traditional observational analysis in the Lifelines Cohort Study (n = 167,785), and performed bi-directional Mendelian randomization (MR) with summary GWAS data from the UK Biobank (n = 350,475) and the International Consortium of Blood Pressure (ICBP)...

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PMID: 38137055
DOI: 10.3390/genes14122233

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