Article
Life-course analysis of a fat mass and obesity-associated (FTO) gene variant and body mass index in the Northern Finland Birth Cohort 1966 using structural equation modeling.
American journal of epidemiology - 15 Sept 2010
Kaakinen Marika, Läärä Esa, Pouta Anneli, Hartikainen Anna-Liisa, Laitinen Jaana, Tammelin Tuija H, Herzig Karl-Heinz, Sovio Ulla, Bennett Amanda J, Peltonen Leena, McCarthy Mark I, Elliott Paul, De Stavola Bianca, Järvelin Marjo-Riitta
Abstract excerpt
The association between variation in the fat mass and obesity-associated (FTO) gene and adulthood body mass index (BMI; weight (kg)/height (m)(2)) is well-replicated. More thorough analyses utilizing phenotypic data over the life course may deepen our understanding of the development of BMI and thus help in the prevention of obesity. The authors used a structural equation modeling approach to explore the network...
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