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Article

Longitudinal replication studies of GWAS risk SNPs influencing body mass index over the course of childhood and adulthood.

PloS one - 1 Jan 2012

Mei Hao, Chen Wei, Jiang Fan, He Jiang, Srinivasan Sathanur, Smith Erin N, Schork Nicholas, Murray Sarah, Berenson Gerald S

Abstract excerpt

Genome-wide association studies (GWAS) have identified multiple common variants associated with body mass index (BMI). In this study, we tested 23 genotyped GWAS-significant SNPs (p-value<5*10-8) for longitudinal associations with BMI during childhood (3-17 years) and adulthood (18-45 years) for 658 subjects. We also proposed a heuristic forward search for the best joint effect model to explain the longitudinal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22355368
DOI: 10.1371/journal.pone.0031470
PMCID: PMC3280302

Genes

FAIM2
FTO
KCTD15
BDNF
MTCH2
TMEM18

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