Article
Relationship between DLEC1 and PBX3 promoter methylation and the risk and prognosis of gastric cancer in peripheral blood leukocytes.
Journal of cancer research and clinical oncology - 1 May 2020
Xie Wenzhen, Zhou Haibo, Han Qian, Sun Tong, Nie Chuang, Hong Jia, Wei Rongrong, Leonteva Anastasiia, Han Xu, Wang Jing, Du Xinyu, Zhu Lin, Zhao Yashuang, Tian Wenjing, Xue Yingwei
Abstract excerpt
PURPOSE: Aberrant DNA methylation could regulate the expression of tumor suppressor gene DLEC1 and oncogene PBX3 and was related to the occurrence and prognosis of gastric cancer (GC). In this study, the associations between DLEC1 and PBX3 promoter methylation in peripheral blood leukocytes (PBLs) and the risk and prognosis of GC were investigated. METHODS: The methylation status of DLEC1 and PBX3 promoter in...
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