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Article

Insulin-like growth factor 2 hypomethylation of blood leukocyte DNA is associated with gastric cancer risk.

International journal of cancer - 1 Dec 2012

Yuasa Yasuhito, Nagasaki Hiromi, Oze Isao, Akiyama Yoshimitsu, Yoshida Shunsuke, Shitara Kouhei, Ito Seiji, Hosono Satoyo, Watanabe Miki, Ito Hidemi, Tanaka Hideo, Kang Daehee, Pan Kai-Feng, You Wei-Cheng, Matsuo Keitaro

Abstract excerpt

To determine whether or not the methylation status of blood leukocyte DNA can be used as a surrogate marker of the risk for cancer, we quantitatively determined the methylation levels of insulin-like growth factor 2 (IGF2) and TUSC3 in 299 gastric cancer cases, and 299 age- and gender-matched controls. The IGF2 methylation levels in blood leukocyte DNA of the cases were lower than those of the healthy controls...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22447362
DOI: 10.1002/ijc.27554

Genes

IGF2
TUSC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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