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Article

A maternal GOT1 novel variant associated with early-onset severe preeclampsia identified by whole-exome sequencing.

BMC medical genetics - 6 Mar 2020

Zhang Lin, Cao Zheng, Feng Fan, Xu Ya-Nan, Li Lin, Gao Hong

Abstract excerpt

BACKGROUND: This study wants to know the genetic cause of preeclampsia (PE) which is a leading cause of maternal and perinatal death, but the underlying molecular mechanisms that cause PE remain poorly understood. Many single nucleotide polymorphisms have been identified by genome-wide association studies and were found to be associated with PE; however, few studies have used whole-exome sequencing (WES) to...

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Identifiers

PMID: 32143588
DOI: 10.1186/s12881-020-0989-2
PMCID: PMC7060644

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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