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The Role of Macrophage Populations in Skeletal Muscle Insulin Sensitivity: Current Understanding and Implications

14 Jul 2023

Abstract excerpt

Insulin resistance is a crucial factor in the development of type 2 diabetes mellitus (T2DM) and other metabolic disorders. Skeletal muscle, the body's largest insulin-responsive tissue, plays a significant role in the pathogenesis of T2DM due to defects in insulin signaling. Recently, there has been growing evidence that macrophages, immune cells essential for tissue homeostasis and injury response, also...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 37511225
DOI: 10.3390/ijms241411467

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