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Article

Mendelian randomisation analysis of circulating adipokines and C-reactive protein on breast cancer risk.

International journal of cancer - 15 Sept 2020

Robinson Timothy, Martin Richard M, Yarmolinsky James

Abstract excerpt

Circulating adipokines and C-reactive protein (CRP) have been linked to breast cancer risk in observational epidemiological studies. The causal nature of these associations is unclear because of the susceptibility of conventional observational designs to residual confounding, reverse causation and other forms of bias. Mendelian randomisation (MR) uses genetic variants as proxies for risk factors to strengthen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32134113
DOI: 10.1002/ijc.32947
PMCID: PMC7497166

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