Article
Characterization of major surface glycoprotein genes of human Pneumocystis carinii and high-level expression of a conserved region.
Infection and immunity - 1 Sept 1998
Mei Q, Turner R E, Sorial V, Klivington D, Angus C W, Kovacs J A
Abstract excerpt
To facilitate studies of Pneumocystis carinii infection in humans, we undertook to better characterize and to express the major surface glycoprotein (MSG) of human P. carinii, an important protein in host-pathogen interactions. Seven MSG genes were cloned from a single isolate by PCR or genomic l...
Topics
- AIDS-Related Opportunistic Infections
- Adult
- Amino Acid Sequence
- Animals
- Antibodies, Fungal
- Antigens, Fungal
- Base Sequence
- Cell Line
- Cloning, Molecular
- Conserved Sequence
- DNA, Fungal
- Fungal Proteins
- Gene Expression
- Genes, Fungal
- Genetic Variation
- Humans
- Membrane Glycoproteins
- Molecular Sequence Data