Article
cDNA sequence diversity and genomic clusters of major surface glycoprotein genes of Pneumocystis carinii.
The Journal of infectious diseases - 1 Oct 1993
Wada M, Kitada K, Saito M, Egawa K, Nakamura Y
Abstract excerpt
The major surface glycoprotein (MSG) of Pneumocystis carinii plays a crucial role in the pathobiology of P. carinii, which often causes fatal pneumonia in AIDS patients. The cDNAs encoding MSG antigens were cloned from a lambda gt11 expression library of rat-derived P. carinii by immunoscreening....
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Antigens, Fungal
- Antigens, Surface
- Cloning, Molecular
- DNA, Fungal
- Fungal Proteins
- Gene Library
- Genes, Fungal
- Genetic Variation
- Membrane Glycoproteins
- Molecular Sequence Data
- Multigene Family
- Oligodeoxyribonucleotides
- Pneumocystis
- Polymerase Chain Reaction
- Rats