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Article

cDNA sequence diversity and genomic clusters of major surface glycoprotein genes of Pneumocystis carinii.

The Journal of infectious diseases - 1 Oct 1993

Wada M, Kitada K, Saito M, Egawa K, Nakamura Y

Abstract excerpt

The major surface glycoprotein (MSG) of Pneumocystis carinii plays a crucial role in the pathobiology of P. carinii, which often causes fatal pneumonia in AIDS patients. The cDNAs encoding MSG antigens were cloned from a lambda gt11 expression library of rat-derived P. carinii by immunoscreening. The cloned cDNAs constituted a gene family containing approximately 70% amino acid identity between subtypes. The...

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Identifiers

PMID: 8376844
DOI: 10.1093/infdis/168.4.979

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Source receipt: pubmed, retrieved 7 Sept 2026.

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