Article
An in vivo and in silico analysis of novel variation in TMBIM6 gene affecting cardiopulmonary traits of Indian goats.
Journal of thermal biology - 1 Feb 2020
Swain Lipi Lekha, Mishra Chinmoy, Sahoo Siddhant Sekhar, Nayak Gangadhar, Pradhan Sukanta Kumar, Mishra Smruti Ranjan, Dige Mahesh
Abstract excerpt
Transmembrane Bax Inhibitor Motif-containing 6 (TMBIM6) gene acts as calcium leak channel and negatively regulates autophagy and autophagosome formation. The TMBIM6 gene was amplified and searched for variation in three different goat populations (i.e. Black Bengal, Ganjam and Raighar) of Odisha state of the India. The result indicated two substitutions i.e. 55th position (C55T) and 95th position (C95A) in the...
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