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A SNP of the COX4I2 gene associated with environmental adaptation in Chinese cattle.

Gene - 30 Jan 2023

Quji Suolang, Wang Shikang, Luosang Danzeng, Li Zhao, Luobu Ciren, Zhuoga Gesang, Li Fuqiang, Xiao Zhengzhong, Lei Chuzhao, Zhuzha Basang

Abstract excerpt

COX4I2 is an isoform of cytochrome C oxidase subunit IV (COX4), which plays an important role in mitochondrial oxidative phosphorylation. This gene affects heat production and thus affects thermoregulatory capacity in mammals. A splice region variant (rs109072064, NC_037340.1:g.61202988C > T) was identified in COX4I2 by using Ensembl, which transforms the amino acid arginine into cysteine in XP_005214921.1. In...

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PMID: 36379384
DOI: 10.1016/j.gene.2022.147043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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