Article
Genetic variations in Hippo pathway genes influence bladder cancer risk in a Chinese population.
Archives of toxicology - 1 Mar 2020
Huang Zhengkai, Wang Xiaolin, Ma Lan, Guo Zheng, Liu Hanting, Du Mulong, Chu Haiyan, Wang Meilin, Wang Zengjun, Zhang Zhengdong
Abstract excerpt
The Hippo pathway participates in development of numerous tumors through regulating tissue growth and cell fate. This study aimed to detect the association between the genetic variants in Hippo pathway genes and bladder cancer risk in a Chinese population. A case-control study of 580 cases and 1101 controls was performed to evaluate the association of single nucleotide polymorphisms (SNPs) in 39 candidate genes...
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