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Genome-wide exploration of genetic interactions for bladder cancer risk.

International journal of cancer - 1 Jan 2024

Yu Evan Yi-Wen, Tang Qiu-Yi, Chen Ya-Ting, Zhang Yan-Xi, Dai Ya-Nan, Wu Yu-Xuan, Li Wen-Chao, Mehrkanoon Siamak, Wang Shi-Zhi, Zeegers Maurice P, Wesselius Anke

Abstract excerpt

Although GWASs have been conducted to investigate genetic variation of bladder tumorigenesis, little is known about genetic interactions that may influence bladder cancer (BC) risk. By leveraging large-scale participants from UK Biobank, we established a discovery database with 4000 Caucasian participants (2000 cases vs 2000 non-cases), a database with 1648 Caucasian participants (824 cases vs 824 non-cases) and...

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Genetic Predisposition to Disease
Genome-Wide Association Study
Polymorphism, Single Nucleotide
Risk Factors
Tumor Suppressor Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Urinary Bladder

Urinary Bladder Neoplasms

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PMID: 37638657
DOI: 10.1002/ijc.34690

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