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Article

An in vitro hyaluronic acid hydrogel based platform to model dormancy in brain metastatic breast cancer cells.

Acta biomaterialia - 15 Apr 2020

Narkhede Akshay A, Crenshaw James H, Crossman David K, Shevde Lalita A, Rao Shreyas S

Abstract excerpt

Breast cancer cells (BCCs) can remain dormant at the metastatic site, which when revoked leads to formation of metastasis several years after the treatment of primary tumor. Particularly, awakening of dormant BCCs in the brain results in breast cancer brain metastasis (BCBrM) which marks the most advanced stage of the disease with a median survival period of ~4-16 months. However, our understanding of dormancy...

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PMID: 32119920
DOI: 10.1016/j.actbio.2020.02.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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