Article
Association between CYP2B6 polymorphism and acute leukemia in a Han population of Northwest China.
Molecular genetics & genomic medicine - 1 May 2020
Yu Li-Li, Zhang Wei, Li Juan, Zhao Li
Abstract excerpt
BACKGROUND: The aim of this study was to investigate potential associations between CYP2B6 c.516G>T polymorphism and the occurrence and prognosis of acute leukemias (AL) in the Han population of Northwest China. METHODS: The CYP2B6 gene polymorphism was analyzed by PCR-RFLP and Sanger DNA sequencing in 126 patients with AL and 161 healthy controls. RESULTS: Compared with controls, there were significantly higher...
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