Article
Association of CYP2B6 G15631T polymorphism with acute leukemia susceptibility.
Leukemia research - 1 Jul 2009
Berköz Mehmet, Yalin Serap
Abstract excerpt
The Cytochrome P450 (CYP) enzymes constitute one of the biggest gene families and play a vital role in the metabolism of endogenous biomolecules, drugs and xenobiotics. One of the members of this family, CYP2B6, plays a very important role in metabolizing carcinogens and medications. CYP2B6G15631T gene polymorphism reduces CYP2B6 enzyme activity. In this study, we aimed to determine whether any association exists...
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