Article
Association of CYP1A1 T3801C (rs4646903) variant with the susceptibility and progression of B-chronic lymphocytic Leukemia (B-CLL) in the Egyptian population.
Gene - 20 Oct 2023
Al-Adl Menna, El-Said Afaf, El-Sebaie Ahmed, Refaat Sherif, Youssef Magdy M
Abstract excerpt
BACKGROUND: The frequency of hematological malignancies is increasing universally, and over the last few decades, a significant increase in the incidence of B-chronic lymphocytic leukemia (B-CLL) has been observed. Many studies have revealed the involvement of genetic predisposition along with environmental exposure to genotoxic xenobiotics in the leukemogenesis process of B-CLL. CYP1A1 is a vital member of the...
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