Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Benchmarking hybrid assemblies of Giardia and prediction of widespread intra-isolate structural variation.

Parasites & vectors - 28 Feb 2020

Pollo Stephen M J, Reiling Sarah J, Wit Janneke, Workentine Matthew L, Guy Rebecca A, Batoff G William, Yee Janet, Dixon Brent R, Wasmuth James D

Abstract excerpt

BACKGROUND: Currently available short read genome assemblies of the tetraploid protozoan parasite Giardia intestinalis are highly fragmented, highlighting the need for improved genome assemblies at a reasonable cost. Long nanopore reads are well suited to resolve repetitive genomic regions resulting in better quality assemblies of eukaryotic genomes. Subsequent addition of highly accurate short reads to long-read...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Protozoan
Share to Genome, Protozoan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Genomics

Share to Giardia

Share to Giardia lamblia

Share to Repetitive Sequences, Nucleic Acid

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 32111234
DOI: 10.1186/s13071-020-3968-8
PMCID: PMC7048089

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Benchmarking hybrid assemblies of Giardia and prediction of widespread intra-isolate structural variation.PMID 32111234Read ↗

Comparative genomics of Giardia duodenalis sub-assemblage AI beaver (Be-2) and human (WB-C6) strains show remarkable homozygosity, sequence similarity, and conservation of VSP genesSemantic proximity Read ↗

Comparative Genomics of Giardia duodenalis Sub-assemblage A1 Beaver (Be-2) and Human (WB-C6) Strains Show Remarkable Homozygosity, Sequence Similarity, and Conservation of VSP GenesSemantic proximity Read ↗

Comparative genomic analyses of freshly isolated Giardia intestinalis assemblage A isolates.Semantic proximity Read ↗

A comparison of short- and long-read whole genome sequencing for microbial pathogen epidemiologySemantic proximity Read ↗

Identification of polymorphic genes for use in assemblage B genotyping assays through comparative genomics of multiple assemblage B Giardia duodenalis isolates.Semantic proximity Read ↗

Benchmarking of real-time, field-deployable whole-genome sequencing of Plasmodium falciparum using Nanopore technology.Semantic proximity Read ↗

Genome analysis and comparative genomics of a Giardia intestinalis assemblage E isolate.Semantic proximity Read ↗

The Giardia lamblia vsp gene repertoire: characteristics, genomic organization, and evolution.Semantic proximity Read ↗

Comparing genomic variant identification protocols for Candida auris.Semantic proximity Read ↗

Genomic survey maps differences in the molecular complement of vesicle formation machinery between Giardia intestinalis assemblages.Semantic proximity Read ↗

Identifying indels from WGS short reads of haploid genomes distinguishes variant-calling algorithmsSemantic proximity Read ↗

ALE: a generic assembly likelihood evaluation framework for assessing the accuracy of genome and metagenome assemblies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.