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Article

The Giardia lamblia vsp gene repertoire: characteristics, genomic organization, and evolution.

BMC genomics - 9 Jul 2010

Adam Rodney D, Nigam Anuranjini, Seshadri Vishwas, Martens Craig A, Farneth Gregory A, Morrison Hilary G, Nash Theodore E, Porcella Stephen F, Patel Rima

Abstract excerpt

BACKGROUND: Giardia lamblia trophozoites colonize the intestines of susceptible mammals and cause diarrhea, which can be prolonged despite an intestinal immune response. The variable expression of the variant-specific surface protein (VSP) genes may contribute to this prolonged infection. Only one is expressed at a time, and switching expression from one gene to another occurs by an epigenetic mechanism. RESULTS:...

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Identifiers

PMID: 20618957
DOI: 10.1186/1471-2164-11-424
PMCID: PMC2996952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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