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Article

Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy

4 Sept 2018

Abstract excerpt

Abstract Fibro-adipogenic progenitors (FAPs) are currently defined by their anatomical position, expression of non-specific membrane-associated proteins, and ability to adopt multiple lineages in vitro. Gene expression analysis at single-cell level reveals that FAPs undergo dynamic transitions through a spectrum of cell states that can be identified by differential expression levels of Tie2 and Vcam1. Different...

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PMID: 30202063
DOI: 10.1038/s41467-018-06068-6

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