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Article

Glucocerebrosidase as a therapeutic target for Parkinson's disease.

Expert opinion on therapeutic targets - 1 Apr 2020

Chen Yu, Sam Richard, Sharma Pankaj, Chen Lu, Do Jenny, Sidransky Ellen

Abstract excerpt

Introduction: The association between Gaucher disease, caused by the inherited deficiency of glucocerebrosidase, and Parkinson's disease was first recognized in the clinic, noting that patients with Gaucher disease and their carrier relatives had an increased incidence of Parkinson's disease. Currently, mutations in glucocerebrosidase (GBA1) are the most common genetic risk factor for Parkinson's disease and...

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Identifiers

PMID: 32106725
DOI: 10.1080/14728222.2020.1733970
PMCID: PMC7113099

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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