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Circulating Glutamine and Alzheimer’s Disease: A Mendelian Randomization Study

1 Feb 2020

Abstract excerpt

Background: Alzheimer’s disease is a devastating neurodegenerative disorder. Its worldwide prevalence is over 24 million and is expected to double by 2040. Finding ways to prevent its cognitive decline is urgent. Methods: A two-sample Mendelian randomization study was performed instrumenting glutamine, which is abundant in blood, capable of crossing the blood-brain barrier, and involved in a metabolic cycle with...

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PMID: 32103921
DOI: 10.2147/cia.s239350

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