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Article

Quantile-dependent expressivity of postprandial lipemia.

PloS one - 1 Jan 2020

Williams Paul T

Abstract excerpt

PURPOSE: "Quantile-dependent expressivity" describes an effect of the genotype that depends upon the level of the phenotype (e.g., whether a subject's triglycerides are high or low relative to its population distribution). Prior analyses suggest that the effect of a genetic risk score (GRS) on fasting plasma triglyceride levels increases with the percentile of the triglyceride distribution. Postprandial lipemia...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32101585
DOI: 10.1371/journal.pone.0229495
PMCID: PMC7043740

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