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Article

Quantile-specific heritability of serum growth factor concentrations.

Growth factors (Chur, Switzerland) - 1 Jan 2000

Williams Paul T

Abstract excerpt

BACKGROUND: "Quantile-dependent expressivity" occurs when the effect size of a genetic variant depends upon whether the phenotype (e.g. growth factor concentration) is high or low relative to its distribution. METHODS: Quantile-regression analysis was applied to family sets from the Framingham Heart Study to determine whether the heritability (h2) of vascular endothelial growth factor (VEGF), hepatocyte growth...

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PMID: 35312415
DOI: 10.1080/08977194.2022.2049261
PMCID: PMC10101221

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