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Article

Ordered patterning of the sensory system is susceptible to stochastic features of gene expression.

eLife - 26 Feb 2020

Giri Ritika, Papadopoulos Dimitrios K, Posadas Diana M, Potluri Hemanth K, Tomancak Pavel, Mani Madhav, Carthew Richard W

Abstract excerpt

Sensory neuron numbers and positions are precisely organized to accurately map environmental signals in the brain. This precision emerges from biochemical processes within and between cells that are inherently stochastic. We investigated impact of stochastic gene expression on pattern formation, focusing on senseless (sens), a key determinant of sensory fate in Drosophila. Perturbing microRNA regulation or...

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Identifiers

PMID: 32101167
DOI: 10.7554/eLife.53638
PMCID: PMC7064346

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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