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Article

Variability in β-catenin pulse dynamics in a stochastic cell fate decision in C. elegans.

Developmental biology - 15 May 2020

Kroll Jason R, Tsiaxiras Jasonas, van Zon Jeroen S

Abstract excerpt

During development, cell fate decisions are often highly stochastic, but with the frequency of the different possible fates tightly controlled. To understand how signaling networks control the cell fate frequency of such random decisions, we studied the stochastic decision of the Caenorhabditis elegans P3.p cell to either fuse to the hypodermis or assume vulva precursor cell fate. Using time-lapse microscopy to...

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Identifiers

PMID: 32032579
DOI: 10.1016/j.ydbio.2020.02.004
PMCID: PMC7203549

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