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Role of Plasmodium falciparum Kelch 13 Protein Mutations in P. falciparum Populations from Northeastern Myanmar in Mediating Artemisinin Resistance.

mBio - 25 Feb 2020

Siddiqui Faiza Amber, Boonhok Rachasak, Cabrera Mynthia, Mbenda Huguette Gaelle Ngassa, Wang Meilian, Min Hui, Liang Xiaoying, Qin Junling, Zhu Xiaotong, Miao Jun, Cao Yaming, Cui Liwang

Abstract excerpt

Mutations in the Plasmodium falciparum Kelch 13 (PfK13) protein are associated with artemisinin resistance. PfK13 is essential for asexual erythrocytic development, but its function is not known. We tagged the PfK13 protein with green fluorescent protein in P. falciparum to study its expression and localization in asexual and sexual stages. We used a new antibody against PfK13 to show that the PfK13 protein is...

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Identifiers

PMID: 32098812
DOI: 10.1128/mBio.01134-19
PMCID: PMC7042691

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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