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Article

Rapid Increase in frequency of gene copy-number variants during experimental evolution in Caenorhabditis elegans.

BMC genomics - 9 Dec 2015

Farslow James C, Lipinski Kendra J, Packard Lucille B, Edgley Mark L, Taylor Jon, Flibotte Stephane, Moerman Donald G, Katju Vaishali, Bergthorsson Ulfar

Abstract excerpt

BACKGROUND: Gene copy-number variation (CNVs), which provides the raw material for the evolution of novel genes, is widespread in natural populations. We investigated whether CNVs constitute a common mechanism of genetic change during adaptation in experimental Caenorhabditis elegans populations. Outcrossing C. elegans populations with low fitness were evolved for >200 generations. The frequencies of CNVs in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crosses, Genetic

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Share to Repetitive Sequences, Nucleic Acid

Source

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Identifiers

PMID: 26645535
DOI: 10.1186/s12864-015-2253-2
PMCID: PMC4673709

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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