The laboratory domestication of Caenorhabditis elegans.

doi:10.1016/j.tig.2015.02.009

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Article

The laboratory domestication of Caenorhabditis elegans.

Trends in genetics : TIG - 1 May 2015

Sterken Mark G, Snoek L Basten, Kammenga Jan E, Andersen Erik C

Abstract excerpt

Model organisms are of great importance to our understanding of basic biology and to making advances in biomedical research. However, the influence of laboratory cultivation on these organisms is underappreciated, and especially how that environment can affect research outcomes. Recent experiments led to insights into how the widely used laboratory reference strain of the nematode Caenorhabditis elegans compares...

Topics

Adaptation, Biological
Alleles
Animals
Caenorhabditis elegans
Gene-Environment Interaction
Genetic Variation
Models, Animal

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Identifiers

PMID: 25804345
DOI: 10.1016/j.tig.2015.02.009
PMCID: PMC4417040

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