Article
Impacts of oocyte/zygote timing for in vitro fertilization and gene editing in the dog.
Theriogenology - 1 Jul 2020
Mukai Chinatsu, Nelson Jacquelyn L, Cheong Soon Hon, Diel de Amorim Mariana, Travis Alexander J
Abstract excerpt
Previously, we reported the first live births of dogs using in vitro fertilization (IVF), embryo cryopreservation, and transfer. These techniques have potential applications in the conservation of endangered canids, and development of gene editing/repair technologies that could improve animal welfare by restoring normal gene function and removing predisposition to disease. Here, we used IVF as a springboard for...
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