Article
Tamoxifen-related endocrine symptoms in Chinese patients with breast cancer: Study protocol clinical trial (SPIRIT Compliant).
Medicine - 1 Feb 2020
Chan Carmen Wing Han, Miaskowski Christine, McCarthy Alexandra, Waye Mary Miu Yee, Yeo Winnie, So Winnie Kwok Wai, Choi Kai Chow, Tsui Stephen Kwok Wing, Chan Judy Yuet Wa
Abstract excerpt
BACKGROUND: Breast cancer is the most prevalent cancer in females and disease recurrence remains a significant problem. To prevent recurrence, tamoxifen is prescribed for at least 5 years. However, among patients who receive tamoxifen, individual responses are highly variable. These responses are affected by the type, frequency, and severity of endocrine symptoms, as well as adherence rates. Polymorphisms in...
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