Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex differences in adult mood and in stress-induced transcriptional coherence across mesocorticolimbic circuitry

6 Feb 2020

Abstract excerpt

Women are approximately two times as likely to be diagnosed with major depressive disorder (MDD) compared to men. While sex differences in MDD might be driven by circulating gonadal hormones, we hypothesized that developmental hormone exposure and/or genetic sex might play a role. Mice were gonadectomized in adulthood to isolate the role of developmental hormones. We examined the effects of developmental gonadal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hormonal Regulation and Hypertension
Share to Stress Responses and Cortisol
Share to Tryptophan and brain disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32066699
DOI: 10.1038/s41398-020-0742-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex differences in adult mood and in stress-induced transcriptional coherence across mesocorticolimbic circuitryPMID 32066699Read ↗

Sex significantly impacts the function of major depression-linked variants <i>in vivo</i>Semantic proximity Read ↗

Sex-specific hormone-sensitive regulatory architecture in adolescence as a scaffold for depression vulnerabilitySemantic proximity Read ↗

Sex Significantly Impacts the Function of Major Depression-Linked Variants In Vivo.Semantic proximity Read ↗

Sex Differences in the Epigenome: A Cause or Consequence of Sexual Differentiation of the Brain?Semantic proximity Read ↗

Sex chromosome complement regulates expression of mood-related genesSemantic proximity Read ↗

Sex differences: Transcriptional signatures of stress exposure in male and female brainsSemantic proximity Read ↗

Multilevel sex-specific neurobiological signatures of early life adversitySemantic proximity Read ↗

Transcriptional dissection of symptomatic profiles across the brain of men and women with depressionSemantic proximity Read ↗

Examining the Intersection of Sex and Stress in Modelling Neuropsychiatric DisordersSemantic proximity Read ↗

Fetal hormonal programming of sex differences in depression: linking women's mental health with sex differences in the brain across the lifespanSemantic proximity Read ↗

Sex Differences in Stress Susceptibility as a Key Mechanism Underlying Depression RiskSemantic proximity Read ↗

Sex differences in DNA methylation may contribute to risk of PTSD and depression: a review of existing evidence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.