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SPsimSeq: semi-parametric simulation of bulk and single-cell RNA-sequencing data

11 Feb 2020

Abstract excerpt

SUMMARY: SPsimSeq is a semi-parametric simulation method to generate bulk and single-cell RNA-sequencing data. It is designed to simulate gene expression data with maximal retention of the characteristics of real data. It is reasonably flexible to accommodate a wide range of experimental scenarios, including different sample sizes, biological signals (differential expression) and confounding batch effects....

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PMID: 32065619
DOI: 10.1093/bioinformatics/btaa105

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